Kono Chemical Industry Co.

1. Introduction

Nonoxynol 9 (nonoxynol) is commonly used as a spermicide for external use. The main method of contraception is to kill the sperm or make the sperm not swim by reducing the surface tension of the lipid membrane of the sperm and changing the osmotic pressure of the sperm so that the sperm cannot enter the cervix and cannot fertilize the egg. After vaginal administration, it can be absorbed by the vaginal mucosa, and after absorption it is widely distributed and excreted in urine and feces.

 

2.Functions

Nonoxynol 9 can kill sperm or cause sperm to not swim.

This is a spermicide for external use.

 

3.Applications

Nonoxynol 9 (nonoxynol) is commonly formulated as suppositories, films, and gels for birth control. Some formulas of this contraceptive can be used in conjunction with condoms, a cervical cap, or a diaphragm.

How to use it?

(1) Nonoxinol Pellicles: 10 minutes before sex, take the film, fold it in half twice or knead it into a soft ball, insert it with your fingers into the vagina, and 10 minutes later have sex. Use a new film for each sexual act.

 

(2) Nonoxynol Gel: Take the gel tube and syringe before sex and connect them. Slowly insert the syringe into the vagina, squeeze out all the gel and remove the syringe. Throw away the tube and syringe together.

 

(3) Nonoxynol suppositories: insert into the vagina 5 minutes before sex.

Caution: If you do not have sex within 30 minutes of taking the medicine, you will need to take the medicine again. Washing 6 hours after sex.

 

4.CP2015 quality standard

Items	Characteristics
Appearance	Viscous, colorless to pale yellow, odorless, can coagulate at temperatures below 10 degrees.
analysis	90.0~110.0 percent
Identification	A. Retention time test B. IR
Free ethylene oxide	Less than or equal to 0.0001 percent
dioxane	Less than or equal to 0.0005 percent
Polyethylene glycol	Less than or equal to 1.6 percent
May indicate	52 degrees ~ 56 degrees
Acid number	Less than or equal to 0.2
Water	Less than or equal to 0.5 percent

 

5. Method of analysis

Chromatographic conditions:

Filler: silica gel bound with octadecylsilane;

Mobile phase: methanol-water (88:12);

Detection wavelength: 280 nm;

Theoretical number: at least 1000.

Determination Method: Take about 0.1g of this product, weigh it accurately, place it in a 100ml volumetric flask, add mobile phase to dissolve and dilute on a balance, shake well and take as a test. solution. Take 10 µl, inject it into a liquid chromatograph and record the chromatogram. Calculated as peak area.

 

6. HPLC

 

7. Stability and security

Stability:

Stable under proper conditions (room temperature). Stability data sheet available upon request.

Safety:

According to research, it is safe for humans.

 

8. Block diagram

 

9. Customer reviews

We have stores on Alibaba, Chemicalbook and LookChem and have received many positive reviews due to our high quality products and unconditional services.

 

10. Our certificate

Over the years, we have been striving to optimize product production and create a quality system. We have created a quality management system and received a certificate for it.

 

11.Our clients

We have established business relationships with Abbott, Unilever, Shiseido, KANS and SIMM, etc.

 

12.Exhibitions

We often participate in international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

http://www.konochems.com/